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Biostatistics (BIOS)


BIOS 200. Med Biostatistics&Epidemiology. 3 Credits.

Introductory design and analysis of medical studies. Epidemiological concepts, case-control and cohort studies. Clinical trials. Students evaluate statistical aspects of published health science studies. Prerequisites: STAT 111, STAT 141 or STAT 143; or STAT 211. Cross-listed with: STAT 200.

BIOS 211. Statistical Methods I. 3 Credits.

Fundamental concepts for data analysis and experimental design. Descriptive and inferential statistics, including classical and nonparametric methods, regression, correlation, and analysis of variance. Statistical software. Prerequisite: Junior standing. Cross-listed with: STAT 211.

BIOS 221. Statistical Methods II. 3 Credits.

Multiple regression and correlation. Basic experimental design. Analysis of variance (fixed random and mixed models). Analysis of covariance. Computer software usage. Cross-listed with: STAT 221.

BIOS 223. Applied Multivariate Analysis. 3 Credits.

Multivariate normal distribution. Inference for mean vectors and covariance matrices. Multivariate analysis of variance (MANOVA), discrimination and classification, principal components, factor analysis. Prerequisite: Any 200 level Statistics course; STAT 221 or STAT 225 recommended; matrix algebra recommended. Cross-listed with: STAT 223.

BIOS 229. Survival Analysis. 3 Credits.

Probabilistic models and inference for time-to-event data. Censored data, life tables, Kaplan-Meier estimation, logrank tests, proportional hazards regression. Specialized applications (e.g. clinical trials, reliability). Prerequisite: Any 200 level Statistics course; one year of calculus. Cross-listed with: STAT 229.

BIOS 231. Experimental Design. 3 Credits.

Randomization, complete and incomplete blocks, cross-overs, Latin squares, covariance analysis, factorial experiments, confounding, fractional factorials, nesting, split plots, repeated measures, mixed models, response surface optimization. Prerequisites: BIOS 211 (BIOS 221 recommended). Cross-listed with: STAT 231.

BIOS 235. Categorical Data Analysis. 3 Credits.

Measures of association and inference for categorical and ordinal data in multiway contingency tables. Log linear and logistic regression models. Prerequisite: BIOS 211. Cross-listed with: STAT 235.

BIOS 241. Statistical Inference. 3 Credits.

Introduction to statistical theory; related probability fundamentals, derivation of statistical principles, and methodology for parameter estimation and hypothesis testing. Pre/co-requisites: BIOS 151, BIOS 153 or BIOS 25; BIOS 141 or equivalent; MATH 121. Cross-listed with: STAT 241.

BIOS 251. Probability Theory. 3 Credits.

Distribution of random variables and functions of random variables. Expectations, stochastic independence, sampling and limiting distributions (central limit theorems). Concepts of random number generation. Pre/co-requisite: MATH 121; STAT 141 or STAT 153 recommended. Cross-listed with: MATH 207, STAT 251.

BIOS 261. Statistical Theory. 3 Credits.

Point and interval estimation, hypothesis testing, and decision theory. Application of general statistical principles to areas such as nonparametric tests, sequential analysis, and linear models. Pre/co-requisites: STAT 251 or either STAT 151 or STAT 153 with Instructor permission. Cross-listed with: STAT 261.